EDUCATION
Fellowship
- Spine Surgery Fellowship, Emory Orthopaedic and Spine Center, Atlanta, GA
Residency
- Orthopaedic Surgery Residency, Harvard University, Boston, MA
Medical School
- University of California San Francisco – School of Medicine
Undergraduate Education
- University of California Berkeley – College of Engineering
Ehsan Saadat, MD
Dr. Ehsan Saadat is a Board-certified, Harvard and Emory-trained orthopaedic spine surgeon. He is an Assistant Professor of Orthopaedic Surgery at Cedars-Sinai Medical Center. His areas of interest include disk replacement and motion-preserving surgery, minimally-invasive microscopic decompression of the cervical and lumbar spine, minimally invasive spinal fusions (XLIF and ALIF), and complex revision spine surgery. Dr. Saadat is the co-director of spine surgery at the Precision Ambulatory Surgery Center in Beverly Hills, where he leads a team of surgeons, anesthesiologists and nurses in delivering state-of-the-art spine care in the outpatient setting.
Dr. Saadat is a prolific and active researcher and an accomplished author, with numerous research publications covering a wide range of topics in orthopaedics and spine surgery. He leads several clinical studies at Cedars-Sinai Medical Center, and is frequently invited to present his work at national and international conferences. Dr. Saadat has authored multiple book chapters, and recently heavily contributed to the newest authoritative textbook of techniques in spine surgery.
Dr. Saadat treats patients not only from southern California, but also from across the United States and around the world.
PUBLICATIONS
Peer-Reviewed
- D Tobert, V Antoci, SP Patel, E Saadat and CM Bono. Adjacent segment disease in the cervical and lumbar spine. Clin Spine Surg. 2017 Apr;30(3):94-101.
- E Saadat, SO Vargas, ME Anderson and M Glotzbecker. Acutely inflamed intra-articular localized tenosynovial giant cell tumor presenting as a septic hip. JBJS Case Connec. 2016 Jul 27; 6 (3): e60.
- JW Brubacher, E Saadat, CM Harper, Y Marjoua and GSM Dyer. Design of a simulation-based curriculum to train orthopaedic residents for disasters in the operating room. Orthop J Harvard Med Sch. 2016 June;17: 49-55.
- AJ Schoenfeld, DA Leonard, E Saadat, CM Bono, MB Harris and ML Ferrone. Predictors of 30- and 90-Day Survival Following Surgical Intervention for Spinal Metastases: A Prognostic Study Conducted at Four Academic Centers. Spine (Phila Pa 1976). 2016 Apr;41(8):E503-9.
- AK Ghori, DA Leonard, AJ Schoenfeld, E Saadat, N Scott, M Ferrone, A Pearson and MB Harris. Modeling one-year survival after surgery on the metastatic spine. Spine J. 2015 July 6; pii: S1529-9430(15)00670-1.
- D Zhang, E Saadat, GSM Dyer and MB Harris. Occupational sharps exposures among orthopaedic surgery residents: a multi-institutional survey study. Orthop J Harvard Med Sch. 2015 June;16: 43-49.
- E Saadat, EJ Curry, X Li and EG Matzkin. Bilateral simultaneous anterior cruciate ligament injury: a case report and national survey of orthopedic surgeon management preference. Orthop Rev (Pavia). 2014 Dec 16;6(4):5551.
- E Saadat, JV Tiberi, Y-M Kwon and DW Burke. Smith-Petersen Vitallium Mold Arthroplasty: 51-year follow-up with histopathologic analysis. JBJS Case Connect. 2013 Oct 09; 3 (4): e112.
- E Saadat, SD Martin, TS Thornhill, S Brownlee, E Losina and JN Katz. Factors predictive of failure of surgical treatment for femoroacetabular impingement: Review of the literature. Am J Sports Med. 2013 Aug 30;42(6):1487-1495.
- B Jobke, R Bolbos, E Saadat, J Cheng, X Li and S Majumdar. Mechanism of disease in early osteoarthritis: application of modern MR imaging techniques – a technical report. Magn Reson Imaging. 2013 Jan;31(1):156-61.
- E Saadat, G Diekmann, S Takemoto and MD Ries. Is an algorithmic approach to the treatment of recurrent dislocation after THA effective? Clin Orth Rel Res. 2012 Feb;470(2):482-9.
- X Li, J Cheng, K Lin, E Saadat, RI Bolbos, MD Ries, A Horvai, TM Link and S Majumdar. Quantitative MRI using T1ρ and T2 in human osteoarthritic cartilage specimens: correlation with biochemical measurements and histology. Magn Reson Imaging. 2011 Apr;29(3):324-34.
- J Zuo, E Saadat, A Romero, K Loo, X Li, TM Link, J Kurhanewicz and S Majumdar. Assessment of Intervertebral Disc Degeneration with Magnetic Resonance Single Voxel Spectroscopy. Magn Res Med. 2009;62(5):1140-6.
- J Lozano, E Saadat, X Li, S Majumdar and CB Ma. Magnetic resonance T(1rho) imaging of osteoarthritis: a rabbit ACL transection model. Magn Reson Imaging. 2009;27(5):611-6.
- E Saadat, B Jobke, B Chu, Y Lu, J Cheng, X Li, MD Ries, S Majumdar and TM Link. Diagnostic performance of in vivo 3T Fast Spin Echo MRI for articular cartilage abnormalities in human osteoarthritic knees using histology as standard of reference. Eur Radiol. 2008;18(10):2292-2302.
- E Saadat, H Lan, S Majumdar, DM Rempel and KB King. Long-term cyclical in vivo loading increases cartilage proteoglycan content in a spatially specific manner: an infrared microspectroscopic imaging and polarized light microscopy study. Arthritis Res Ther. 2006;8(5):R147.
Non-Peer Reviewed
Invited Review Article:
- RA Ravisnky, EJ Crawford, A Rasouli and E Saadat. Posterior cervical foraminotomy. Seminars in Spine Surgery 2020;31(1).
- E Saadat and S Majumdar. Magnetic Resonance Imaging of cartilage: Detecting early degeneration and monitoring post-operative improvement. US Musculoskeletal Review 2007; June:16-18.
Book Chapters:
- E Saadat, JM Rhee, JG Heller. Anterior cervical discectomy and fusion. In “Emory Illustrated Tips and Tricks in Spine Surgery,” JM Rhee (Ed), Lippincot Williams and Wilkins (in press).
- E Saadat, JM Rhee, JG Heller. Posterior cervical laminoplasty. In “Emory Illustrated Tips and Tricks in Spine Surgery,” JM Rhee (Ed), Lippincot Williams and Wilkins (in press).
- E Saadat, JM Rhee, JG Heller. Posterior cervical foraminotomy. In “Emory Illustrated Tips and Tricks in Spine Surgery,” JM Rhee (Ed), Lippincot Williams and Wilkins (in press).
- E Saadat, D Ananthakrishnan, KW Michael, B Horton. Percutaneous thoracic fusion and pedicle screw instrumentation. In “Emory Illustrated Tips and Tricks in Spine Surgery,” JM Rhee (Ed), Lippincot Williams and Wilkins (in press).
- E Saadat, ST Yoon and SD Boden. Posterior lumbar fusion and pedicle screw instrumentation. In “Emory Illustrated Tips and Tricks in Spine Surgery,” JM Rhee (Ed), Lippincot Williams and Wilkins (in press).
- E Saadat, ST Yoon and SD Boden. Open transforaminal lumbar interbody fusion. In “Emory Illustrated Tips and Tricks in Spine Surgery,” JM Rhee (Ed), Lippincot Williams and Wilkins (in press).
- E Saadat, ST Yoon and SD Boden. Anterior lumbar interbody fusion. In “Emory Illustrated Tips and Tricks in Spine Surgery,” JM Rhee (Ed), Lippincot Williams and Wilkins (in press).
- E Saadat and KW Michael. Application of Halo, Mayfield head holder and Gardner-Wells tongs. In “Emory Illustrated Tips and Tricks in Spine Surgery,” JM Rhee (Ed), Lippincot Williams and Wilkins (in press).
- E Saadat and KW Michael. Operative treatment of thoracolumbar burst fractures. In “Emory Illustrated Tips and Tricks in Spine Surgery,” JM Rhee (Ed), Lippincot Williams and Wilkins (in press).
- E Saadat, JG Heller and S Presciutti. Dural repair. In “Emory Illustrated Tips and Tricks in Spine Surgery,” JM Rhee (Ed), Lippincot Williams and Wilkins (in press).
- E Saadat, JG Heller and S Presciutti. Neuromonitoring alert during spinal surgery. In “Emory Illustrated Tips and Tricks in Spine Surgery,” JM Rhee (Ed), Lippincot Williams and Wilkins (in press).
- E Saadat and P Wright. Pathology of the child’s cervical spine and its clinical implications. In “The Management of Disorders of the Child’s Cervical Spine,” JH Phillips, DJ Hedequist, SA Shah and B Yaszay (Eds), Springer Publishing (2018).
- E Saadat and TD Cha. Disc degeneration and pain in the lumbar spine. In “Orthopaedic Knowledge Update 12,” J Grauer (Ed), American Academy of Orthopaedic Surgeons (2017).
- E Saadat, FJ Hornicek and JH Schwab. Surgical management of metastatic lesions of the cervical spine. In “Cirugía de la Columna Cervical,” R Gonzalez Diaz and H Koller (Eds), Editorial Medica Panamericana (2015).
- E Saadat and TD Cha. Interspinous process distraction. In “Decision Making in Degenerative Spinal Surgery,” K Singh, S Qureshi (Eds), Nova (2015).
- AK Ghori, T Herzog, E Saadat and A White. PET scanning in spine surgery in clinical decision support. In “Spine Surgery,” A Vaccaro, S Prasad, J Rihn, M Wang (Eds), Decision Support in Medicine LLC (2014).
- E Saadat, TM Link and CB Ma. Current Magnetic Resonance Imaging techniques for clinical diagnosis and staging of knee osteoarthritis. In “Advances in MRI of the Knee for Osteoarthritis,” S Majumdar (Ed), World Scientific Publishing Co (2010).
- E Saadat and TM Link. Current radiographic diagnosis for osteoarthritis of the knee. In “Advances in MRI of the Knee for Osteoarthritis,” S Majumdar (Ed), World Scientific Publishing Co (2010).
- E Saadat, RI Bolbos and MD Ries. Clinical presentation and natural history of osteoarthritis. In “Advances in MRI of the Knee for Osteoarthritis,” S Majumdar (Ed), World Scientific Publishing Co (2010).
PRESENTATIONS
Oral Presentations (Regional, National and International Conferences):
- E Saadat, A Rasouli, A Ma, J Cuellar, W Wagner: Analysis of safety and risk profile of anterior lumbar surgery in ambulatory surgery centers. February 2020, International Society for Advancement of spine Surgery, 2020 Annual Meeting, Puerto Rico.
- E Saadat, A Rasouli, A Ma, S Sun, Z Tang, J Tang, T Perry, S Kim, J Gold, S Yang, R Yumul, J Smith, B Croft, K Thordarson, E Robertsen, R Fridman, A Emanuel, B Mjos: Reduction of length-of-stay after spinal fusion: effectiveness of the perioperative surgical home with progression of care model compared to national length-of-stay index. February 2020, International Society for Advancement of spine Surgery, 2020 Annual Meeting, Puerto Rico.
- E Saadat, J Cuellar, A Ma, M Eng, P Hill, M Krop, T Lanman, E Nomoto, B Perri, K Siddique, S Stephan, A Wong, W Wagner, A Rasouli: Outpatient vs inpatient anterior lumbar surgery: a multi-site, comparative analysis of patient safety. January 2020, Cedars-Sinai 19th Annual Symposium on Current Concepts in Spinal Disorders, Las Vegas, NV.
- E Saadat, S Sun, Z Tang, S Yang, J Tang, T Perry, SD Kim, J Gold, H Sax, R Yumul, J Smith, B Mjos, A Emuel, B Croft, K Thordarson, A Ma, E Robertsen, R Fridman, A Rasouli: Assessment of the effect of implementation of enhanced recovery after surgery program in spinal surgical procedures: a retrospective study. September 2019, North American Spine Society, 2019 Annual Meeting, Chicago, IL.
- E Saadat. Innovation in American medicine: outpatient spine surgery. July 2019, Japanese Orthopaedic Association Traveling Fellows Academic Conference, Cedars-Sinai Medical Center, Los Angeles, CA.
- E Saadat. Current concepts in spinal surgery. May 2019, Iranian Medical Society, May 2019 Meeting, Los Angeles, CA.
- E Saadat. Posterior surgical options for multilevel cervical spinal cord compression: the role of laminoplasty. March 2019, NASS Spine Section – Society for Brain Mapping and Therapeutics, 16th Annual World Congress, Los Angeles, CA.
- E Saadat. Comprehensive spinal and neurologic exam and correlation to clinical diagnosis. May 2018, Northridge Family Medicine Residency Education Lecture Series, Northridge Hospital Medical Center, Northridge, CA.
- E Saadat. Imaging algorithm and differential diagnosis for back/leg pain. May 2018, Continuing Medical Education Lecture Series, Northridge Hospital Medical Center, Northridge, CA.
- E Saadat. Imaging algorithm and differential diagnosis for back/leg pain. May 2017, Emory University School of Medicine Primary Care Update CME course: Office Orthopaedics, Sports Medicine and Spine Problems, Atlanta, GA.
- E Saadat, DA Leonard, AK Ghori, N Scott, CM Bono, AP White, ML Ferrone and MB Harris: Timing of diagnosis of metastatic disease to the spine as a predictor for post-surgical survival. March 2016, American Academy of Orthopaedic Surgeons, 2016 Annual Meeting, Orlando, FL.
- AJ Schoenfeld, DA Leonard, E Saadat, CM Bono, MB Harris and ML Ferrone: Predictors of 30- and 90-Day Survival Following Surgical Intervention for Spinal Metastases: A Prognostic Study Conducted at Four Academic Centers. March 2016, American Academy of Orthopaedic Surgeons, 2016 Annual Meeting, Orlando, FL.
- AK Ghori, DA Leonard, E Saadat, CM Bono, AP White, ML Ferrone and MB Harris: Modeling one-year survival after surgery on the metastatic spine. October 2015, North American Spine Society, 29th Annual Meeting, Chicago, IL.
- E Saadat, G Diekmann, S Takemoto and MD Ries: Comparative assessment of surgical interventions for treatment of recurrent dislocation after total hip arthroplasty. February 2011, American Academy of Orthopaedic Surgeons, 2011 Annual Meeting, San Diego, CA.
- E Saadat, G Diekmann, S Takemoto and MD Ries: Comparative assessment of surgical interventions for treatment of recurrent dislocation after total hip arthroplasty. September 2010, The Hip Society, 2010 Summer Scientific Meeting, New York, NY.
- J Zuo, E Saadat, A Romero, K Loo, X Li and S Majumdar: Identification of Magnetic Resonance spectroscopic markers for intervertebral disc degeneration in cadaveric spines and correlation to biochemical findings. February 2009, Orthopaedic Research Society, 55th Annual Meeting, Las Vegas, NV.
- J Cheng, E Saadat, RI Bolbos, B Jobke, SM Siddiqui, MD Ries, TM Link and S Majumdar: Detection of Proteoglycan Content in Human Osteoarthritic Cartilage Samples with Magnetic Resonance T1rho Imaging. May 2008, International Society for Magnetic Resonance in Medicine, 16th Scientific Meeting and Exhibition, Toronto, Ontario, Canada.
- J Zuo, E Saadat, X Li and S Majumdar: MR spectroscopy in intact and degenerated bovine intervertebral disc. May 2008, International Society for Magnetic Resonance in Medicine, 16th Scientific Meeting and Exhibition, Toronto, Ontario, Canada.
- J Zuo, E Saadat, X Li and S Majumdar: Single voxel spectroscopy of intervertebral disc degeneration – An in vitro bovine disc degeneration model. March 2008, Orthopaedic Research Society, 54th Annual Meeting, San Francisco, CA.
- E Saadat, S Majumdar, DM Rempel and KB King: The effect of amplitude and frequency of in vivo loading on proteoglycan content of rabbit articular cartilage. March 2008, Orthopaedic Research Society, 54th Annual Meeting, San Francisco, CA.
Poster Presentations (Regional, National and International Conferences):
- E Saadat, A Ma, J Cuellar, T Lanman, A Rasouli: Analysis of safety and risk profile of single- and multi-level cervical artificial disc replacements in ambulatory surgery centers. February 2020, International Society for Advancement of spine Surgery, 2020 Annual Meeting, Puerto Rico.
- E Saadat, DA Leonard, AK Ghori, N Scott, CM Bono, AP White, ML Ferrone and MB Harris: Timing of diagnosis of metastatic disease to the spine as a predictor for post-surgical survival. March 2017, AO Spine Fellow’s Forum, Banff, Canada
- JW Brubacher, E Saadat, Y Marjoua, CM Harper and GSM Dyer: Design of a simulation-based curriculum to train orthopaedic residents for disasters in the operating room. June 2016, American Orthopaedic Association, 2016 Annual Meeting and Leadership Conferences. Seattle, WA.
- J Zuo, E Saadat, A Romero, K Loo, TM Link and S Majumdar: MR Spectroscopy in intervertebral disc and correlation with biochemical analysis. April 2009, International Society for Magnetic Resonance in Medicine, 17th Scientific Meeting and Exhibition, Honolulu, HI.
- E Saadat, J Zuo, A Romero, K Loo, X Li and S Majumdar: Identification of MR spectroscopic markers for intervertebral disc degeneration in cadaveric spines and correlation to biochemical findings. September 2008, 5th Annual UCSF Imaging Research Symposium, San Francisco, CA.
- B Jobke, RI Bolbos, E Saadat, J Cheng, X Li and S Majumdar: Initial pathomechanisms in osteoarthritis: advances in new MR imaging techniques (T1rho). March 2008, Orthopaedic Research Society, 54th Annual Meeting, San Francisco, CA.
- E Saadat, RI Bolbos, J Cheng, B Jobke, MD Ries, S Majumdar and X Li: Detection of proteoglycan depletion in human osteoarthritic cartilage samples with magnetic resonance T1rho imaging. December 2007, Osteoarthritis Research Society International, 2007 World Congress on Osteoarthritis, Ft Lauderdale, FL.
- E Saadat, B Jobke, J Cheng, X Li, RI Bolbos, MD Ries, S Majumdar and TM Link: Diagnostic performance of in vivo MRI for articular cartilage abnormalities in human osteoarthritic knees using histology with Safranin-O staining as standard of reference. December 2007, Osteoarthritis Research Society International, 2007 World Congress on Osteoarthritis, Ft Lauderdale, FL.
- J Cheng, B Jobke, E Saadat, RI Bolbos, MD Ries, TM Link, X Li and S Majumdar: Local correlation between in vivo MR T1ρ mapping and biochemistry and histology in osteoarthritic articular cartilage. December 2007, Osteoarthritis Research Society International, 2007 World Congress on Osteoarthritis, Ft Lauderdale, FL.
- E Saadat, B Jobke, J Cheng, X Li, RI Bolbos, MD Ries, S Majumdar and TM Link: Diagnostic performance of in vivo MRI for articular cartilage abnormalities in human osteoarthritic knees using histology with Safranin-O staining as standard of reference. September 2007, 4th Annual UCSF Imaging Research Symposium, San Francisco, CA.
- E Saadat, RI Bolbos, J Cheng, B Jobke, MD Ries, S Majumdar and X Li: Detection of proteoglycan depletion in human osteoarthritic cartilage with Magnetic Resonance T1r Imaging. June 2007, 8th Annual University of California Systemwide Bioengineering Symposium, UCSF, San Francisco, CA.
- J Cheng, B Jobke, E Saadat, RI Bolbos, MD Ries, TM Link, X Li and S Majumdar: Regional correlation between in vivo T1rho mapping and histology and biochemistry in osteoarthritic articular cartilage. June 2007, 8th Annual University of California Systemwide Bioengineering Symposium, UCSF, San Francisco, CA.
- E Saadat, S Majumdar, A Burghardt, and KB King: Cyclical in vivo loading increases cartilage proteoglycan content in the rabbit metacarpophalangeal joint. March 2006, Orthopaedic Research Society, 52nd Annual Meeting, Chicago, IL.